IHC of TAG-72 on an FFPE Breast Carcinoma Tissue
|For In Vitro Diagnostic Use
|Summary and Explanation
|Tumor-associated glycoprotein (TAG-72) has been shown to be expressed in a wide variety of epithelial malignant tissues. TAG-72 antigen is a high molecular glycoprotein found on the surface of many cancer cells, including breast, colon and pancreatic cells. It is present in human Adenocarcinomas and in lesser amounts, non-neoplastic tissues. The majority of human Adenocarcinomas including Colorectal, Pancreatic, Gastric, Ovarian, Endometrial, Mammary, and Non-Small Cell Lung Cancer display some cell populations that are positive for TAG-72. TAG-72 has also been found to be useful for the distinction between Mesothelioma and Adenocarcinoma; however, false positive reactions can occur so results must be interpreted with the utmost caution.
|TAG-72 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
|Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.