CA15-3 – MMab

SKU: 5d8e1dc344cd Categories: , , , ,


IHC of CA15-3 on an FFPE Breast Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationThis antibody has been used for evaluating the primary site of a metastatic carcinoma of unknown origin and distinguishing between benign and malignant lesions. It is believed that CA15-3 reacts primarily with the DF3-antigen, a 300 kDa mucin-like glycoprotein present on the apical border of secretory mammary epithelial cells. CA15-3 has been detected with immunohistochemistry in a wide spectrum of carcinomas, including Breast Carcinomas (ductal and lobular), Sarcomas (Synovial Sarcoma and Malignant Fibrous Histiocytomas), and Lung Carcinomas. CA15-3 can be used as a supplementary marker for epithelial differentiation. CA15-3 does not stain Melanomas or Ewing’s Sarcomas. Approximately 30% of Hepatocellular Carcinomas are positive for CA15-3.
Antibody TypeMouse MonoclonalCloneDF3
IsotypeIgG1ReactivityParaffin, Frozen
LocalizationCytoplasmic, MembranousControlKidney, Breast, Pancreas, Lymph Node, Cervix, Salivary Gland, Bladder TCC
PresentationCA15-3 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5099PredilutedReady-To-Use3.0 ml
BSB 5100PredilutedReady-To-Use7.0 ml
BSB 5101PredilutedReady-To-Use15.0 ml
BSB 5102Concentrated1:250-1:10000.1 ml
BSB 5103Concentrated1:250-1:10000.5 ml
BSB 5104Concentrated1:250-1:10001.0 ml
BSB 5105Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content