Products

Calcitonin – Rabbit Polyclonal

Calcitonin

IHC of Calcitonin on an FFPE Thyroid Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Calcitonin is a 32-amino acid polypeptide hormone that is produced in humans primarily by C-cells located in the thyroid, and in many other animals in the ultimobranchial gland. It acts to reduce blood calcium (Ca2+), opposing the eff ects of parathyroid hormone (PTH). It has been found in fi sh, reptiles, birds, and mammals. Its importance in humans has not been as well established as in other animals. Immunohistochemical staining with Calcitonin antibody has proven to be an effective way of demonstrating the existence of Calcitonin-producing cells in the thyroid. C-cell Hyperplasia and Medullary Thyroid Carcinomas stain positive for Calcitonin. Studies of Calcitonin have resulted in the identifi cation of a wide spectrum of C-cell proliferative abnormalities.
Antibody Type Rabbit Polyclonal Clone N/A
Isotype N/A Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Thyroid, Medullary Carcinoma of Thyroid
Presentation Calcitonin is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5113 Prediluted Ready-To-Use 3.0 ml
BSB 5114 Prediluted Ready-To-Use 7.0 ml
BSB 5115 Prediluted Ready-To-Use 15.0 ml
BSB 5116 Concentrated 1:100-1:500 0.1 ml
BSB 5117 Concentrated 1:100-1:500 0.5 ml
BSB 5118 Concentrated 1:100-1:500 1.0 ml
BSB 5119 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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