Myelin Basic Protein – Rabbit Polyclonal

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Ihc Of Myelin Basic Protein On An Ffpe Brain Tissue

IHC of Myelin Basic Protein on an FFPE Brain Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationMyelin Basic Protein (MBP) is a protein believed to be important in the process of myelination of nerves in the central nervous system (CNS). The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of post-translational modifications on the protein, which include phosphorylation, methylation, deamidation and citrullination.MBP has been demonstrated in Neuromas, Neurofibromas, and Neurogenic Sarcomas. However, other spindle-cell neoplasms do not stain with this antibody. Immunoreactivity for MBP in Granular-cell Tumors strengthens the concept of a Schwann-cell derivation of these lesions. Unlike other nervous system proteins such as GFAP and S-100, MBP has not been demonstrated in melanocytes or tumors derived from them.
Antibody TypeRabbit PolyclonalCloneN/A
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlBrain, Neuroblastoma
PresentationMyelin Basic Protein is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5778PredilutedReady-To-Use3.0 ml
BSB 5779PredilutedReady-To-Use7.0 ml
BSB 5780PredilutedReady-To-Use15.0 ml
BSB 5781Concentrated1:100-1:5000.1 ml
BSB 5782Concentrated1:100-1:5000.5 ml
BSB 5783Concentrated1:100-1:5001.0 ml
BSB 5784Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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