Macrophage/HAM-56 – MMab

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Ihc Of Macrophage On An Ffpe Liver Tissue

IHC of Macrophage on an FFPE Liver Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationMacrophages comprise many forms of mononuclear phagocytes found in tissues that derive from hematopoietic stem cells in the bone marrow. Among the functions of macrophages are nonspecific phagocytosis and pinocytosis, killing of ingested microorganisms, and digestion and presentation of antigens to T and B-lymphocytes. Macrophages work to secrete a large number of diverse products such as lysozyme and collagenases, several complement components and coagulation factors, some prostaglandins and leukotrienes, and many regulatory molecules (Interferon, Interleukin 1). Macrophage HAM-56 reacts with tingible macrophages (found in the germinal centers of lymph nodes), interdigitating macrophages of lymph nodes and tissue macrophages, (e.g., Kupffer cells of the liver and alveolar macrophages of the lung). This antibody also stains a subpopulation of endothelial cells, most prominently those of the capillaries and smaller blood vessels. HAM-56 reacts with monocytes, but is unreactive with B and T-lymphocytes.
Antibody TypeMouse MonoclonalCloneHAM-56
IsotypeIgM/KReactivityParaffin, Frozen
LocalizationCytoplasmicControlTonsil, Lymph Node
PresentationMacrophage HAM-56 is a mouse monoclonal antibody derived from cell culture supernatant that isconcentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5736PredilutedReady-To-Use3.0 ml
BSB 5737PredilutedReady-To-Use7.0 ml
BSB 5738PredilutedReady-To-Use15.0 ml
BSB 5739Concentrated1:250-1:10000.1 ml
BSB 5740Concentrated1:250-1:10000.5 ml
BSB 5741Concentrated1:250-1:10001.0 ml
BSB 5742Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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