Claudin-1 – Rabbit Polyclonal

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Claudin1 20X 1Mde29 28 2 Skin

IHC of Claudin-1 on an FFPE Skin Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationClaudin 1 is an integral membrane protein and a component of tight junction strands. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.
Claudin-1 stains membraines of cells and is found in nearly all carcinomas, with stains much stronger in carcinoma cells than in normal tissue cells.
Antibody TypeRabbit PolyclonalClonePolyclonal
IsotypeIgGReactivityParaffin, Frozen
LocalizationMembranous, CytoplasmicControlSkin, Small intestine. Perineurioma, Neurofibroma, colon Carcinoma
PresentationClaudin 1 is a Rabbit Polyclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6562PredilutedReady-To-Use3.0 ml
BSB 6563PredilutedReady-To-Use7.0 ml
BSB 6564PredilutedReady-To-Use15.0 ml
BSB 6565Concentrated1:50-1:2000.1 ml
BSB 6566Concentrated1:50-1:2000.5 ml
BSB 6567Concentrated1:50-1:2001.0 ml
BSB 6568Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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