Products

CD99 – MMab

IHC of CD99 on an FFPE Ewing’s Sarcoma Tissue

IHC of CD99 on an FFPE Ewing’s Sarcoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation CD99, also known as MIC-2 or single-chain Type-1 glycoprotein, is a human protein encoded by the CD99 gene. The protein has a MW of 32 kD. It is expressed on all leukocytes but highest on thymocytes, and is believed to augment T-cell adhesion and apoptosis of double-positive T-cells. It also participates in migration and activation. The CD99 antigen is found on the cell membrane of Ewing’s Sarcoma and Primitive Peripheral Neuroectodermal Tumors (PNET). It is also present on a variety of other cell types including bone marrow, lymph nodes, spleen, cortical thymocytes, granulosa cells of the ovary, beta cells, CNS ependymal cells, Sertoli’s cells of the testis and a few endothelial cells. Mature granulocytes, however, tend to express very little or no CD99. MIC-2 has also been identified in Lymphoblastic Lymphoma, Rhabdomyosarcoma, Mesenchymal Chondrosarcoma, and Thymoma.
Antibody Type Mouse Monoclonal Clone BSB-9
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Pancreas, Thymus, Ependyma, Ewing’s Sarcoma
Presentation CD99 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5309 Prediluted Ready-To-Use 3.0 ml
BSB 5310 Prediluted Ready-To-Use 7.0 ml
BSB 5311 Prediluted Ready-To-Use 15.0 ml
BSB 5312 Concentrated 1:25-1:100 0.1 ml
BSB 5313 Concentrated 1:25-1:100 0.5 ml
BSB 5314 Concentrated 1:25-1:100 1.0 ml
BSB 5315 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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