Vimentin – RMab

IHC of Vimentin on an FFPE Melanoma Tissue

IHC of Vimentin on an FFPE Melanoma Tissue

Specification Sheets
Safety Data Sheet


Intended Use For In Vitro Diagnostic Use
Summary and Explanation Vimentin is a member of the intermediate filament family of proteins. Intermediate filaments are an important structural feature of eukaryotic cells. Together with microtubules and actin microfilaments, they make up the cytoskeleton.
Expression of vimentin, when used in conjunction with keratin, is helpful in distinguishing melanomas from Undifferentiated Carcinomas and Large-Cell Lymphomas. All Melanomas and Schwannomas react strongly with vimentin. This antibody recognizes a 57 kDa intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymph cells, endothelial cells and fibroblasts. Non-reactivity of vimentin antibody is often considered more useful than its presence, since there are a few tumors that do not contain vimentin (e.g., Hepatoma and Seminoma).
Antibody Type Rabbit Monoclonal Clone EP21
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Tonsil, Lymph Node, Colon
Presentation Vimentin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2307 Prediluted Ready-To-Use 3.0 ml
BSB 2308 Prediluted Ready-To-Use 7.0 ml
BSB 2309 Prediluted Ready-To-Use 15.0 ml
BSB 2310 Concentrated 1:50-1:200 0.1 ml
BSB 2311 Concentrated 1:50-1:200 0.5 ml
BSB 2312 Concentrated 1:50-1:200 1.0 ml
BSB 2313 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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