Vimentin – RMab

Ihc Of Vimentin On An Ffpe Melanoma Tissue

IHC of Vimentin on an FFPE Melanoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationVimentin is a member of the intermediate filament family of proteins. Intermediate filaments are an important structural feature of eukaryotic cells. Together with microtubules and actin microfilaments, they make up the cytoskeleton.
Expression of vimentin, when used in conjunction with keratin, is helpful in distinguishing melanomas from Undifferentiated Carcinomas and Large-Cell Lymphomas. All Melanomas and Schwannomas react strongly with vimentin. This antibody recognizes a 57 kDa intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymph cells, endothelial cells and fibroblasts. Non-reactivity of vimentin antibody is often considered more useful than its presence, since there are a few tumors that do not contain vimentin (e.g., Hepatoma and Seminoma).
Antibody TypeRabbit MonoclonalCloneEP21
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlTonsil, Lymph Node, Colon
PresentationVimentin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2307PredilutedReady-To-Use3.0 ml
BSB 2308PredilutedReady-To-Use7.0 ml
BSB 2309PredilutedReady-To-Use15.0 ml
BSB 2310Concentrated1:50-1:2000.1 ml
BSB 2311Concentrated1:50-1:2000.5 ml
BSB 2312Concentrated1:50-1:2001.0 ml
BSB 2313Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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