Tyrosinase – MMab

SKU: 687d834eeb16 Categories: , ,

Mart-1 &Amp; Tyrosinase

IHC of Tyrosinase on an FFPE Malignant Melanoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationTyrosinase is an enzyme that catalyzes the oxidation of phenols (such as tyrosine) and is widespread in plants and animals. Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. The gene for Tyrosinase is regulated by the Microphthalmia-associated transcription factor. A mutation in the tyrosinase gene leads to impaired tyrosinase production resulting in Type I Oculocutaneous Albinism, a hereditary disease that affects 1 in 17,000 people in the U.S.Anti-Tyrosinase has been found to be quite specific for melanotic lesions such as Malignant Melanoma and Melanotic Neurofibroma. Essentially no carcinomas express this marker.
Antibody TypeMouse MonoclonalCloneBSB-6
IsotypeIgG2aReactivityParaffin, Frozen
LocalizationCytoplasmicControlSkin, Malignant Melanoma
PresentationAnti-Tyrosinase is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6008PredilutedReady-To-Use3.0 ml
BSB 6009PredilutedReady-To-Use7.0 ml
BSB 6010PredilutedReady-To-Use15.0 ml
BSB 6011Concentrated1:50-1:2000.1 ml
BSB 6012Concentrated1:50-1:2000.5 ml
BSB 6013Concentrated1:50-1:2001.0 ml
BSB 6014Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content