Vimentin – MMab

Ihc Of Vimentin On An Ffpe Cervix Tissue

IHC of Vimentin on an FFPE Cervix Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationVimentin is a member of the intermediate filament family of proteins. Intermediate filaments are an important structural feature of eukaryotic cells. Together with microtubules and actin microfilaments, they make up the cytoskeleton. Expression of vimentin, when used in conjunction with keratin, is helpful in distinguishing melanomas from Undifferentiated Carcinomas and Large-Cell Lymphomas. All Melanomas and Schwannomas react strongly with vimentin. This antibody recognizes a 57 kDa intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymph cells, endothelial cells and fibroblasts. Non-reactivity of vimentin antibody is often considered more useful than its presence, since there are a few tumors that do not contain vimentin (e.g., Hepatoma and Seminoma).
Antibody TypeMouse MonoclonalCloneV9
IsotypeIgG1/KReactivityParaffin, Frozen
LocalizationCytoplasmicControlTonsil, Lymph Node
PresentationVimentin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6022PredilutedReady-To-Use3.0 ml
BSB 6023PredilutedReady-To-Use7.0 ml
BSB 6024PredilutedReady-To-Use15.0 ml
BSB 6025Concentrated1:250-1:10000.1 ml
BSB 6026Concentrated1:250-1:10000.5 ml
BSB 6027Concentrated1:250-1:10001.0 ml
BSB 6028Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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