Synaptophysin – RMab

Ihc Of Synaptophysin On An Ffpe Pancreas Tissue

IHC of Synaptophysin on an FFPE Pancreas Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationSynaptophysin is a synaptic vesicle glycoprotein weighing 38 kDa. It is present in endocrine cells, the brain, spinal cord, and adrenal glands. It acts as a marker for neuroendocrine cells.
Synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas and gastrointestinal mucosa. Positive staining is seen in neurons of the brain, spinal cord, retina, and Paneth’s cells in the gastrointestinal tract and gastric parietal cells. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely-granular cytoplasmic staining is observed and probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of Synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Synaptophysin is an independent broad-range marker of neural and neuroendocrine differentiation.
Antibody TypeRabbit MonoclonalCloneEP158
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlPancreas, Brain, Pituitary, Adrenal, Colon
PresentationSynaptophysin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2237PredilutedReady-To-Use3.0 ml
BSB 2238PredilutedReady-To-Use7.0 ml
BSB 2239PredilutedReady-To-Use15.0 ml
BSB 2240Concentrated1:100-1:5000.1 ml
BSB 2241Concentrated1:100-1:5000.5 ml
BSB 2242Concentrated1:100-1:5001.0 ml
BSB 2243Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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