Spectrin – MMab

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Ihc Of Spectrin On An Ffpe Bone Marrow Tissue

IHC of Spectrin on an FFPE Bone Marrow Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationSpectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming scaffolds and playing an important role in maintenance of plasma- membrane integrity and cytoskeletal structure. The hexagonal arrangements are formed by tetramers of spectrin associating with short actin filaments at either end of the tetramer. These short actin filaments act as junctional complexes, allowing the formation of the hexagonal mesh. Spectrin is found in the intracellular side of the plasma membrane of many cell types found in muscles, red blood cells and red cell precursors. Anti-Spectrin antibody is useful in the diagnosis of Erythroid Leukemias.
Antibody TypeMouse MonoclonalCloneRBC2/3D5
IsotypeIgG2b/KReactivityParaffin, Frozen
LocalizationMembranousControlBone Marrow, Spleen
PresentationAnti-Spectrin is a Mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5938PredilutedReady-To-Use3.0 ml
BSB 5939PredilutedReady-To-Use7.0 ml
BSB 5940PredilutedReady-To-Use15.0 ml
BSB 5941Concentrated1:25-1:1000.1 ml
BSB 5942Concentrated1:25-1:1000.5 ml
BSB 5943Concentrated1:25-1:1001.0 ml
BSB 5944Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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