Beta-Catenin – MMab


IHC of Beta-Catenin on an FFPE Breast Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationBeta-Catenin is a subunit of the Cadherin protein complex. Cadherins are a type of protein normally expressed on the surface of certain cells. Specifi cally, Beta Cateinin is a 92 kDa protein normally found in the cytoplasm of the cell in the sub-membranous location. This protein is associated with E-Cadherin and may be essential for the function of E-Cadherin. Mutations in the Beta-Catenin gene result in the nuclear accumulation of this protein. Nuclear accumulation of this protein has been demonstrated in Fibromatosis lesions of the breast and abdomen, and therefore is useful in diff erentiating this lesion from other spindle-cell lesions that may occur in these locations.
Antibody TypeMouse MonoclonalClone14
IsotypeIgG1ReactivityParaffin, Frozen
LocalizationCytoplasmic, Membranous, NuclearControlFibromatosis of the Breast and Abdomen
PresentationBeta-Catenin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5085PredilutedReady-To-Use3.0 ml
BSB 5086PredilutedReady-To-Use7.0 ml
BSB 5087PredilutedReady-To-Use15.0 ml
BSB 5088Concentrated1:50-1:2000.1 ml
BSB 5089Concentrated1:50-1:2000.5 ml
BSB 5090Concentrated1:50-1:2001.0 ml
BSB 5091Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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