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PAX-2 – RMab

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IHC of PAX-2 on an FFPE Kidney Tissue

IHC of PAX-2 on an FFPE Kidney Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use.
Summary and ExplanationPAX-2 is a homeogene strongly expressed during kidney development. PAX-2 gene is expressed in the metanephric mesenchyma after ureter bud induction and is a key factor for the mesenchyma-epithelium conversion. Animals transgenic for PAX-2 have severe renal abnormalities and cysts but no solid tumoral features.Anti-PAX-2 can be used to distinguish Ovarian Serous Papillary Carcinoma (PAX-2 positive) from Primary Breast Carcinoma (PAX-2 negative). It can also be used to distinguish Clear Cell Renal Carcinoma (positive) from Hepatocellular Carcinoma
(negative).
Antibody TypeRabbit MonoclonalCloneEP235
IsotypeIgGReactivityParaffin, Frozen
LocalizationNuclearControlKidney, Fallopian Tube, Clear Cell Renal Carcinoma, Ovarian Serous Papillary Carcinoma
PresentationPAX-2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2566PredilutedReady-To-Use3.0 ml
BSB 2567PredilutedReady-To-Use7.0 ml
BSB 2568PredilutedReady-To-Use15.0 ml
BSB 2569Concentrated1:50-1:2000.1 ml
BSB 2570Concentrated1:50-1:2000.5 ml
BSB 2571Concentrated1:50-1:2001.0 ml
BSB 2572Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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