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Myogenin – MMab

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IHC of Myogenin on an FFPE Rhabdomyosarcoma Tissue

IHC of Myogenin on an FFPE Rhabdomyosarcoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Myogenin is a transcription factor active in muscles. In particular, it is a myogenic regulatory factor. Myogenin is a member of a family of myogenic regulatory genes, which includes MyoD, myf5 and MRF4. These genes encode a set of transcription factors which are essential for muscle development. Expression of myogenin is restricted to cells of skeletal-muscle origin. It is, therefore, a useful marker for tumors of the muscle lineage, being strongly expressed in Alveolar Rhabdomyosarcomas. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of Rhabdomyosarcoma and some Leiomyosarcomas. Positive nuclear staining may occur in Wilm’s Tumor.
Antibody Type Mouse Monoclonal Clone F5D
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Nuclear Control Rhabdomyosarcoma
Presentation Myogenin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated,dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5792 Prediluted Ready-To-Use 3.0 ml
BSB 5793 Prediluted Ready-To-Use 7.0 ml
BSB 5794 Prediluted Ready-To-Use 15.0 ml
BSB 5795 Concentrated 1:100-1:500 0.1 ml
BSB 5796 Concentrated 1:100-1:500 0.5 ml
BSB 5797 Concentrated 1:100-1:500 1.0 ml
BSB 5798 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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