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Granzyme B – Rabbit Polyclonal

Ihc Of Granzyme B On An Ffpe Tonsil Tissue

IHC of Granzyme on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationGranzymes are exogenous serine proteases that are released by cytoplasmic granules within cytotoxic T-cells and natural killer cells. Their purpose is to induce apoptosis within virus-infected cells, thus destroying them. Anti-Granzyme B antibodies have been useful in diagnosing Natural Killer/T-cell Lymphoma, as well as Anaplastic Large Cell Lymphoma. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin’s Disease.
Antibody TypeRabbit PolyclonalCloneN/A
IsotypeN/AReactivityParaffin, Frozen
LocalizationCytoplasmic (Granular)ControlLiver, Testis, Cervix, Tonsil, Lymph Node, Spleen
PresentationGranzyme B is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5589PredilutedReady-To-Use3.0 ml
BSB 5590PredilutedReady-To-Use7.0 ml
BSB 5591PredilutedReady-To-Use15.0 ml
BSB 5592Concentrated1:25-1:1000.1 ml
BSB 5593Concentrated1:25-1:1000.5 ml
BSB 5594Concentrated1:25-1:1001.0 ml
BSB 5595Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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