IHC of Glycophorin A on an FFPE Bone Marrow Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Glycophorins A (GPA) and B (GPB) are single pass membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin-like surface and it has been suggested this provides a barrier to cell fusion, thus minimizing aggregation between red blood cells in the circulation. Anti-Glycophorin A has been used to characterize erythroid cell development and in the diagnosis of Erythroid Leukemias. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Mouse Monoclonal | Clone | GA-R2 | |||||||||||||||||||||||||||||||||
| Isotype | IgG2b/K | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Membranous | Control | Bone Marrow, Placenta, Tonsil, Liver, Prostate, Adrenal, Spleen, Colon, Pancreas, Fallopian Tube | |||||||||||||||||||||||||||||||||
| Presentation | Anti-Glycophorin A is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
