GCDFP-15 – MMab

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Gcdfp Mmab

IHC of GCDFP-15 on an FFPE Breast Carcinoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationGross Cystic Disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross Cystic Disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP-15. The cells within the body that produce GCDFP-15 appear to be restricted primarily to those with apocrine function such as breast cysts and in apocrine glands in the axilla, vulva, eyelid, and ear canal. Studies have found GCDFP-15 to be a highly specific and sensitive marker for breast cancer. Approximately 70% of breast carcinomas stain positive with antibody to GCDFP-15. In contrast, Colorectal Carcinomas, as well as Mesotheliomas, do not stain with this antibody. Lung Adenocarcinomas rarely stain with this antibody.
Antibody TypeMouse MonoclonalClone23A3
IsotypeIgG2aReactivityParaffin, Frozen
LocalizationCytoplasmicControlBreast, Salivary Gland, Breast Carcinoma, Sweat Glands in Skin
PresentationGCDFP-15 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5554PredilutedReady-To-Use3.0 ml
BSB 5555PredilutedReady-To-Use7.0 ml
BSB 5556PredilutedReady-To-Use15.0 ml
BSB 5557Concentrated1:100-1:5000.1 ml
BSB 5558Concentrated1:100-1:5000.5 ml
BSB 5559Concentrated1:100-1:5001.0 ml
BSB 5560Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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