FOXP3 – RMab

3. Ihc Of Foxp3 On A Ffpe Thymus Tissue Webpage

IHC of FOXP3 on an FFPE Thymus Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and Explanation

FOXP3, also known as scurfin, is a protein involved in immune system responses. A member of the forkhead box protein family, FOXP3 appears to function as a transcription factor in the development and function of regulatory T cells. In regulatory T cell model systems, the FOXP3 transcription factor occupies the promoters of many important for regulatory T-cell function, and may repress transcription of key genes following stimulation of T cell receptors.

Alterations in numbers of regulatory T-cells – in particular those that express FOXP3 – are found in a number of disease states. Patients with tumors have a local relative excess of FOXP3 positive T cells which inhibits the body’s ability to suppress the formation of cancerous cells.

Antibody TypeRabbit MonoclonalCloneEP340
IsotypeIgGReactivityParaffin, Frozen
LocalizationNuclearControlTonsil, Lymph Node, Thymus
PresentationFOXP3 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2922PredilutedReady-To-Use3.0 ml
BSB 2923PredilutedReady-To-Use7.0 ml
BSB 2924PredilutedReady-To-Use15.0 ml
BSB 2925Concentrated1:25-1:1000.1 ml
BSB 2926Concentrated1:25-1:1000.5 ml
BSB 2927Concentrated1:25-1:1001.0 ml
BSB 2928Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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