Cytokeratin 4 – RMab

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Cytokeratin 4

IHC of Cytokeratin 4 on an FFPE Oral Mucosa Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCytokeratin 4 is a type II cytokeratin and is specifically found in differentiated layers of the mucosal and esophageal epithelia together with Cytokeratin 13. Mutations in the genes encoding this protein (KRT4) have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia.
A decreased expression of CK4 is associated with head and neck squamous carcinoma. It is helpful in the differentiation of squamous cell carcinoma of esophagus origin from that of thyroid origin.
Antibody TypeRabbit MonoclonalCloneEP4
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlCornea, Anus, Larynx, Pharynx, Tongue, Prostate, tonsil, Cervix, Squamous Epithelium, of Esophagus, Cervical Squamous Carcinomas
PresentationCK4 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6590PredilutedReady-To-Use3.0 ml
BSB 6591PredilutedReady-To-Use7.0 ml
BSB 6592PredilutedReady-To-Use15.0 ml
BSB 6593Concentrated1:25-1:1000.1 ml
BSB 6594Concentrated1:25-1:1000.5 ml
BSB 6595Concentrated1:25-1:1001.0 ml
BSB 6596Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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