CD7 – RMab

SKU: 33dd026d00de Categories: , , ,

Cd7 Rmab-Alt

IHC of CD7 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin gene superfamily. It is expressed in the majority of immature and mature T-lymphocytes and T-cell Leukemia. CD7 is also found in natural killer cells, a small subpopulation of normal B-cells and in malignant B-cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interactions during early lymphoid development.
CD7 is a consistently-expressed T-cell antigen in Lymphoblastic Lymphomas and Leukemias; therefore, it is a useful marker in the identification of such neoplastic proliferations. CD7 is expressed in the majority of mature peripheral T-cells, the majority of post-thymic T-cells, NK cells, some myeloid cells, T-cell Acute Lymphoblastic Leukemia/Lymphoma, Acute Myelogenous Leukemia and Chronic Myelogenous Leukemia. Interestingly, CD7 is conspicuously absent in adult T-cell Leukemia/Lymphoma and is not expressed in Sezary cells.
Antibody TypeRabbit MonoclonalCloneEP132
IsotypeIgGReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node, Colon, Liver, Spleen, Bone Marrow, Lymphoblastic, Lymphoma
PresentationCD7 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2321PredilutedReady-To-Use3.0 ml
BSB 2322PredilutedReady-To-Use7.0 ml
BSB 2323PredilutedReady-To-Use15.0 ml
BSB 2324Concentrated1:50-1:2000.1 ml
BSB 2325Concentrated1:50-1:2000.5 ml
BSB 2326Concentrated1:50-1:2001.0 ml
BSB 2327Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content