CD7 – MMab

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Ihc Of Cd7 On An Ffpe Tonsil Tissue

IHC of CD7 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin gene superfamily. It is expressed in the majority of immature and mature T-lymphocytes, and T-cell Leukemia. It is also found in natural killer cells, a small subpopulation of normal B-cells and in malignant B-cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. CD7 is a consistently-expressed T-cell antigen in Lymphoblastic Lymphomas and Leukemias; therefore, it is a useful marker in the identification of such neoplastic proliferations. CD7 is expressed in the majority of mature peripheral T-cells, the majority of post-thymic T-cells, NK cells, some myeloid cells, T-cell Acute Lymphoblastic Leukemia/Lymphoma, Acute Myelogenous Leukemia and Chronic Myelogenous Leukemia. Interestingly, CD7 is conspicuously absent in adult T-cell Leukemia/Lymphoma and is not expressed in Sezary cells.
Antibody TypeMouse MonoclonalCloneLP15
IsotypeIgG2bReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node
PresentationCD7 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5162PredilutedReady-To-Use3.0 ml
BSB 5163PredilutedReady-To-Use7.0 ml
BSB 5164PredilutedReady-To-Use15.0 ml
BSB 5165Concentrated1:25-1:1000.1 ml
BSB 5166Concentrated1:25-1:1000.5 ml
BSB 5167Concentrated1:25-1:1001.0 ml
BSB 5168Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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