CD23 – RMab

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Cd23 Rmab

IHC of CD23 on an FFPE Lymphoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD23, also known as Fc epsilon RII, is the “low affinity” receptor for IgE, an antibody isotype involved in allergy and (arguably) resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B-cells, activated macrophages, eosinophils, follicular dendritic cells and platelets.
This is a B-cell antibody that is useful for differentiating between B-CLL and B-SLL’s that are CD23-positive from Mantle-cell Lymphomas and Small-Cleaved Lymphomas that are CD23- negative. This antibody reacts with the antigen that is found on a subpopulation of peripheral blood cells, B-lymphocytes and on EBV-transformed B-lymphoblastoid cell lines.
Antibody TypeRabbit MonoclonalCloneEP75
IsotypeIgGReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node
PresentationCD23 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6471PredilutedReady-To-Use3.0 ml
BSB 6472PredilutedReady-To-Use7.0 ml
BSB 6473PredilutedReady-To-Use15.0 ml
BSB 6474Concentrated1:50-1:2000.1 ml
BSB 6475Concentrated1:50-1:2000.5 ml
BSB 6476Concentrated1:50-1:2001.0 ml
BSB 6477Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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