Androgen Receptor – MMab

SKU: abcd6bbd2c55 Categories: , , , ,


IHC of Androgen on a FFPE Prostate Tissue

United States
Research Use
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationThe androgen receptor (AR) is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone. The main function of the androgen receptor is as a DNA-binding transcription factor which regulates gene expression. However, the androgen receptor has additional functions independent of DNA binding. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and the brain. This antibody reacts with the androgen receptor and also with the newly-described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors. Abnormalities in the AR-signaling pathway have been linked to a number of diseases, including Prostate Cancer, Kennedy’s Disease and male infertility.
Antibody TypeMouse MonoclonalCloneBSB-4
IsotypeIgG1ReactivityParaffin, Frozen
LocalizationNuclearControlProstate, Prostatic Adenocarcinoma
PresentationAndrogen receptor is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6071PredilutedReady-To-Use3.0 ml
BSB 6072PredilutedReady-To-Use7.0 ml
BSB 6073PredilutedReady-To-Use15.0 ml
BSB 6074Concentrated1:100-1:5000.1 ml
BSB 6075Concentrated1:100-1:5000.5 ml
BSB 6076Concentrated1:100-1:5001.0 ml
BSB 6077Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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