Alpha-Fetoprotein – RMab

Alpha-Fetoprotein Rmab

IHC of AFP on a FFPE Yolk-Sac Carcinoma Tissue

United States
Research Use
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationAlpha-fetoprotein (AFP) is a protein which in humans is encoded by the AFP gene. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. This protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4.
Positive staining with this antibody is seen in hepatocytes of fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a Yolk-Sac Carcinoma, or one of a few other tumors. In conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in Yolk-Sac Carcinomas in gonadal and extragonadal sites of hepatic malignancies and a few other neoplasms.
Antibody TypeRabbit MonoclonalCloneEP209
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlFetal Liver, Hepatocellular Carcinoma
PresentationAFP is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2384PredilutedReady-To-Use3.0 ml
BSB 2385PredilutedReady-To-Use7.0 ml
BSB 2386PredilutedReady-To-Use15.0 ml
BSB 2387Concentrated1:100-1:5000.1 ml
BSB 2388Concentrated1:100-1:5000.5 ml
BSB 2389Concentrated1:100-1:5001.0 ml
BSB 2390Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content