Alpha-Fetoprotein – RMab

SKU: 8d6a7ea8eef4 Categories: , , , ,

Alpha-Fetoprotein RMab

IHC of AFP on a FFPE Yolk-Sac Carcinoma Tissue

United States
Research Use
Safety Data Sheet


Intended Use For In Vitro Diagnostic Use
Summary and Explanation Alpha-fetoprotein (AFP) is a protein which in humans is encoded by the AFP gene. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. This protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4.
Positive staining with this antibody is seen in hepatocytes of fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a Yolk-Sac Carcinoma, or one of a few other tumors. In conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in Yolk-Sac Carcinomas in gonadal and extragonadal sites of hepatic malignancies and a few other neoplasms.
Antibody Type Rabbit Monoclonal Clone EP209
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Fetal Liver, Hepatocellular Carcinoma
Presentation AFP is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2384 Prediluted Ready-To-Use 3.0 ml
BSB 2385 Prediluted Ready-To-Use 7.0 ml
BSB 2386 Prediluted Ready-To-Use 15.0 ml
BSB 2387 Concentrated 1:100-1:500 0.1 ml
BSB 2388 Concentrated 1:100-1:500 0.5 ml
BSB 2389 Concentrated 1:100-1:500 1.0 ml
BSB 2390 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content