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ACTH – MMab

Category:
Intended Use For In Vitro Diagnostic Use
Summary and Explanation Adrenocorticotropic Hormone (ACTH or corticotropin) is a polypeptide hormone synthesized from POMC, (Pro-opiomelanocortin) and secreted from corticotropes in the anterior lobe of the pituitary gland in response to Corticotropin-releasing Hormone (CRH) released by the hypothalamus. It consists of 39 amino acids. ACTH is a useful marker in the classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs), as well as other tumors (e.g.,some Small-Cell Carcinomas present in lung tissue) causing Paraneoplastic Syndromes by secreting ACTH.
Antibody Type Mouse Monoclonal Clone BSB-25
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Normal Pituitary
Presentation ACTH is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5015 Prediluted Ready-To-Use 3.0 ml
BSB 5016 Prediluted Ready-To-Use 7.0 ml
BSB 5017 Prediluted Ready-To-Use 15.0 ml
BSB 5018 Concentrated 1:250-1:1000 0.1 ml
BSB 5019 Concentrated 1:250-1:1000 0.5 ml
BSB 5020 Concentrated 1:250-1:1000 1.0 ml
BSB 5021 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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