| Intended Use |
For In Vitro Diagnostic Use |
|
| Summary and Explanation |
Adrenocorticotropic Hormone (ACTH or corticotropin) is a polypeptide hormone synthesized from POMC, (Pro-opiomelanocortin) and secreted from corticotropes in the anterior lobe of the pituitary gland in response to Corticotropin-releasing Hormone (CRH) released by the hypothalamus. It consists of 39 amino acids. ACTH is a useful marker in the classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs), as well as other tumors (e.g.,some Small-Cell Carcinomas present in lung tissue) causing Paraneoplastic Syndromes by secreting ACTH. |
|
Antibody Type |
Mouse Monoclonal |
Clone |
BSB-25 |
|
Isotype |
IgG1/K |
Reactivity |
Paraffin, Frozen |
|
Localization |
Cytoplasmic |
Control |
Normal Pituitary |
|
| Presentation |
ACTH is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. |
|
| Availability |
| Catalog No. |
Antibody Type |
Dilution |
Volume/QTY |
| BSB 5015 |
Prediluted |
Ready-To-Use |
3.0 ml |
| BSB 5016 |
Prediluted |
Ready-To-Use |
7.0 ml |
| BSB 5017 |
Prediluted |
Ready-To-Use |
15.0 ml |
| BSB 5018 |
Concentrated |
1:250-1:1000 |
0.1 ml |
| BSB 5019 |
Concentrated |
1:250-1:1000 |
0.5 ml |
| BSB 5020 |
Concentrated |
1:250-1:1000 |
1.0 ml |
| BSB 5021 |
Control Slides |
|
5 |
|
|
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. |
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