Villin – MMab

Ihc Of Villin On An Ffpe Colon Tissue

IHC of Villin on an FFPE Colon Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationVillin is an actin-binding protein that contains gelsolin domains capped by a ”headpiece” consisting of a fast and independently-folding three-helix bundle stabilized by hydrophobic interactions. The headpiece domain is a commonly-studied protein in molecular dynamics due to its fast-folding kinetics and short primary sequence. It is a regulator of the actin cytoskeleton and is expressed mainly in the brush border in animals.
Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium. This antibody has been useful in differentiating Gastrointestinal Adenocarcinoma, Neuroendocrine Carcinomas and Ovarian Adenocarcinomas from Adenocarcinomas of other organs. Also labeled by this antibody are Merkel cells of the skin.
Antibody TypeMouse MonoclonalCloneCWWB1
IsotypeIgG1ReactivityParaffin, Frozen
LocalizationCytoplasmic MembranousControlKidney, Colon, Small Bowel Mucosa, Colonic Mucosa
PresentationAnti-Villin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6015PredilutedReady-To-Use3.0 ml
BSB 6016PredilutedReady-To-Use7.0 ml
BSB 6017PredilutedReady-To-Use15.0 ml
BSB 6018Concentrated1:25-1:1000.1 ml
BSB 6019Concentrated1:25-1:1000.5 ml
BSB 6020Concentrated1:25-1:1001.0 ml
BSB 6021Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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