Spectrin – RMab

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Ihc Of Spectrin On An Ffpe Fallopian Tube Tissue

IHC of Spectrin on an FFPE Fallopian Tube Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use.
Summary and Explanation
Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming scaffolds and playing an important role in maintenance of plasma- membrane integrity and cytoskeletal structure. The hexagonal arrangements are formed by tetramers of spectrin associating with short actin filaments at either end of the tetramer. These short actin filaments act as junctional complexes, allowing the formation of the hexagonal mesh.
Spectrin is found in the intracellular side of the plasma membrane of many cell types found in muscles, red blood cells and red cell precursors. Anti-Spectrin antibody is useful in the diagnosis of Erythroid Leukemias and it may be a superior marker to  Glycophorin for the identification of erythroid precursors.
Antibody TypeRabbitt MonoclonalCloneEP 251
IsotypeIgGReactivityParaffin, Frozen
Bone Marrow, Spleen
PresentationSpectrin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2587PredilutedReady-To-Use3.0 ml
BSB 2588PredilutedReady-To-Use7.0 ml
BSB 2589PredilutedReady-To-Use15.0 ml
BSB 2590Concentrated1:50-1:2000.1 ml
BSB 2591Concentrated1:50-1:2000.5 ml
BSB 2592Concentrated1:50-1:2001.0 ml
BSB 2593Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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