SOX-11 – MMab

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Ihc Of Sox-11 On An Ffpe Mantle Cell Lymphoma Tissue

IHC of SOX-11 on an FFPE Mantle Cell Lymphoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationTranscription factor SOX-11 is a member of the group C SOX (SRY-related HMG-box) transcription factor family involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis and adult neurogenesis. SOX-11 is normally expressed in the developing human central nervous system, Medulloblastoma, and Glioma.
Anti-SOX-11 nuclear protein expression is highly associated with both Cyclin D1-positive and negative Mantle Cell Lymphomas, with a stronger and more homogeneous Immunohistochemistry staining than Cyclin D1.
Antibody TypeMouse MonoclonalCloneCL0142
IsotypeIgG2aReactivityParaffin, Frozen
LocalizationNuclearControlMantle Cell Lymphoma
PresentationSOX-11 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2216PredilutedReady-To-Use3.0 ml
BSB 2217PredilutedReady-To-Use7.0 ml
BSB 2218PredilutedReady-To-Use15.0 ml
BSB 2219Concentrated1:25-1:1000.1 ml
BSB 2220Concentrated1:25-1:1000.5 ml
BSB 2221Concentrated1:25-1:1001.0 ml
BSB 2222Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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