Somatostatin – MMab

Ihc Of Somatostatin On An Ffpe Pancreas Tissue

IHC of Somatostatin on a FFPE Pancreas Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and Explanation

Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and by inhibition of the release of numerous secondary hormones. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids; the other of 28 amino acids. Somatostatin is secreted not only by cells of the hypothalamus but also by the stomach, intestine, and delta cells of the pancreas. It binds to somatostatin receptors.

Somatostatin is a useful marker of D-cells of pancreatic islet cells. D-cells are used to identify hyperplasia of the pancreatic islets. Most of these tumors are malignant, giving rise to Somatostatinomas. Somatostatin suppresses gastric acid secretion, gallbladder contractions and pancreatic enzyme secretion.

Antibody TypeMouse MonoclonalCloneBSB-113
IsotypeIgG2a/KReactivityParaffin, Frozen
LocalizationCytoplasmicControlPancreas, Colon, Adrenal, Brain
PresentationSomatostatin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 3413PredilutedReady-To-Use3.0 ml
BSB 3414PredilutedReady-To-Use7.0 ml
BSB 3415PredilutedReady-To-Use15.0 ml
BSB 3416Concentrated1:250-1:10000.1 ml
BSB 3417Concentrated1:250-1:10000.5 ml
BSB 3418Concentrated1:250-1:10001.0 ml
BSB 3419Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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