Ihc Of Psap On An Ffpe Prostate Tissue

IHC of PSAP on an FFPE Prostate Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationProstatic specific acid phosphatase (PSAP) is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of acid phosphatase are found in metastasized prostate cancer. Diseases of the bone, such as Paget’s disease or hyperparathyroidism, diseases of blood cells, (such as Sickle-Cell Disease), Multiple Myeloma or Lysosomal Storage Diseases, (such as
Gaucher’s disease), will show moderately increased levels. Certain medications can cause temporary increases or decreases in acid phosphatase levels. Manipulation of the prostate gland through massage, biopsy or rectal exam before a test may increase the levels of PSAP.
This antibody reacts with prostatic specific acid phosphatase in the glandular epithelium of the normal and Hyperplastic Prostate, Carcinoma of the prostate and metastatic cells of Prostatic Carcinoma. This marker may be helpful in pinpointing the site of origin in cases of Metastatic Carcinoma of the prostate, and is considered a more sensitive marker than PSA. However, it also offers less specificity.
Antibody TypeRabbit MonoclonalCloneEP53
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlProstate, Prostatic Adenocarcinoma
PresentationPSAP is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2147PredilutedReady-To-Use3.0 ml
BSB 2148PredilutedReady-To-Use7.0 ml
BSB 2149PredilutedReady-To-Use15.0 ml
BSB 2150Concentrated1:50-1:2000.1 ml
BSB 2151Concentrated1:50-1:2000.5 ml
BSB 2152Concentrated1:50-1:2001.0 ml
BSB 2153Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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