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MyoD1 – RMab

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IHC of MyoD1 on an FFPE Rhabydomyosarcoma Tissue

IHC of MyoD1 on an FFPE Rhabydomyosarcoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation MyoD1 belongs to a family of proteins known as myogenic regulatory factors (MRFs) and has a key role in regulating muscle differentation. These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MyoD1 is expressed in activated satellite cells, but not in quiescent satellite cells. In development, MyoD1 commits mesoderm cells to a skeletal lineage, and then regulates that process. It may also play a role in muscle repair.
In abnormal tissues, MyoD1 labels tumor cells in Rhabdomyosarcoma and is one of the earliest markers of myogenic commitment.
Antibody Type Rabbit Monoclonal Clone EP212
Isotype IgG Reactivity Paraffin, Frozen
Localization Nuclear Control Fetal Muscle, Rhabdomyosarcoma
Presentation MyoD1 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6974 Prediluted Ready-To-Use 3.0 ml
BSB 6975 Prediluted Ready-To-Use 7.0 ml
BSB 6976 Prediluted Ready-To-Use 15.0 ml
BSB 6977 Concentrated 1:50-1:200 0.1 ml
BSB 6978 Concentrated 1:50-1:200 0.5 ml
BSB 6979 Concentrated 1:50-1:200 1.0 ml
BSB 6980 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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