MyoD1 – RMab

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Ihc Of Myod1 On An Ffpe Rhabydomyosarcoma Tissue

IHC of MyoD1 on an FFPE Rhabydomyosarcoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationMyoD1 belongs to a family of proteins known as myogenic regulatory factors (MRFs) and has a key role in regulating muscle differentation. These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MyoD1 is expressed in activated satellite cells, but not in quiescent satellite cells. In development, MyoD1 commits mesoderm cells to a skeletal lineage, and then regulates that process. It may also play a role in muscle repair.
In abnormal tissues, MyoD1 labels tumor cells in Rhabdomyosarcoma and is one of the earliest markers of myogenic commitment.
Antibody TypeRabbit MonoclonalCloneEP212
IsotypeIgGReactivityParaffin, Frozen
LocalizationNuclearControlFetal Muscle, Rhabdomyosarcoma
PresentationMyoD1 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6974PredilutedReady-To-Use3.0 ml
BSB 6975PredilutedReady-To-Use7.0 ml
BSB 6976PredilutedReady-To-Use15.0 ml
BSB 6977Concentrated1:50-1:2000.1 ml
BSB 6978Concentrated1:50-1:2000.5 ml
BSB 6979Concentrated1:50-1:2001.0 ml
BSB 6980Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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