Myelin Basic Protein – RMab

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Mbp Rmab

IHC of Myelin Basic Protein on an FFPE Brain Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationMyelin Basic Protein (MBP) is a protein believed to be important in the process of myelination of nerves in the central nervous system (CNS). The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of post-translational modifications on the protein, which include phosphorylation, methylation, deamidation and citrullination.MBP has been demonstrated in Neuromas, Neurofibromas, and Neurogenic Sarcomas. However, other spindle-cell neoplasms do not stain with this antibody. Immunoreactivity for MBP in Granular-cell Tumors strengthens the concept of a Schwann-cell derivation of these lesions. Unlike other nervous system proteins such as GFAP and S-100, MBP has not been demonstrated in melanocytes or tumors derived from them.
Antibody TypeRabbit MonoclonalCloneEP207
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlBrain, Neuroblastoma
PresentationMyelin Basic Protein is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6960PredilutedReady-To-Use3.0 ml
BSB 6961PredilutedReady-To-Use7.0 ml
BSB 6962PredilutedReady-To-Use15.0 ml
BSB 6963Concentrated1:25-1:1000.1 ml
BSB 6964Concentrated1:25-1:1000.5 ml
BSB 6965Concentrated1:25-1:1001.0 ml
BSB 6966Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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