Mammaglobin – RMab

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Ihc Of Mammaglobin On An Ffpe Breast Tissue

IHC of Mammagloblin on an FFPE Breast Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationMammaglobin is a gene that encodes a 10 kDa glycoprotein. In humans, expression of the gene is limited to the adult mammary gland. A correlation between increased expression of the gene and Breast Cancer has been reported. Mammaglobin mRNA is present in high levels in human Breast Cancer cell lines and primary Breast Cancers. High levels of mRNA have been detected in normal human sweat glands as well, but are absent in Sweat Gland Tumors. Anti-Mammaglobin (31A5) has been shown to be effective in detecting up to 85% of Breast Carcinomas using immunohistochemical techniques. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of Breast Cancer patients have shown that mammaglobin is a highly-specific marker and correlates with several prognostic factors, such as lymph node involvement.
Antibody TypeRabbit MonoclonalCloneEP249
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlBreast, Skin, Fallopian Tube, Breast Carcinoma
PresentationAnti-Mammaglobin (31A5) is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5743PredilutedReady-To-Use3.0 ml
BSB 5744PredilutedReady-To-Use7.0 ml
BSB 5745PredilutedReady-To-Use15.0 ml
BSB 5746Concentrated1:25-1:1000.1 ml
BSB 5747Concentrated1:25-1:1000.5 ml
BSB 5748Concentrated1:25-1:1001.0 ml
BSB 5749Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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