IHC of HLA-DR alpha-chain on an FFPE Lymphoma Tissue
|Intended Use||For In Vitro Diagnostic Use|
|Summary and Explanation||HLA class II histocompatibility antigen, DR alpha chain (HLA-DR alpha chain) is a polymorphic cell surface glycoprotein that is crucial for the cellular interaction in the immune system. Class II molecules have limited tissue distribution and are predominantly expressed on B lymphocytes and macrophage; these class II molecules present peptides derived from extracellular porteins to T cells.
HLA-DR alpha chain antibody labels B cells, dendritic cells, monocytes and macrophages. It is also reported to react with tumor cells in many types of cancers including breast, liver, lung and ovary cancer.
|Antibody Type||Rabbit Monoclonal||Clone||EP96|
|Presentation||HLA-DR Alpha Chain is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.|
|Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.|