IHC of HLA-DR alpha-chain on an FFPE Lymphoma Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | HLA class II histocompatibility antigen, DR alpha chain (HLA-DR alpha chain) is a polymorphic cell surface glycoprotein that is crucial for the cellular interaction in the immune system. Class II molecules have limited tissue distribution and are predominantly expressed on B lymphocytes and macrophage; these class II molecules present peptides derived from extracellular porteins to T cells. HLA-DR alpha chain antibody labels B cells, dendritic cells, monocytes and macrophages. It is also reported to react with tumor cells in many types of cancers including breast, liver, lung and ovary cancer. |
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| Antibody Type | Rabbit Monoclonal | Clone | EP96 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Tonsil, Spleen | |||||||||||||||||||||||||||||||||
| Presentation | HLA-DR Alpha Chain is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
