Histone H3 Phospho – Rmab

Ihc Of Histone H3 Phospho On An Ffpe Nh Lymphoma Tissue

IHC of Histone H3 Phospho on an FFPE NH Lymphoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and Explanation
Phosphohistone-H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucelosomes of the “beads on a string” structure. In mammalian cells, phosphohistone H3 is negligible during interphase but reaches a maximum for chromatin condensation during mitosis.
Phosphohistone-H3 can serve as a mitotic marker to separate mitotic figures fromapoptotic bodies and karyorrhectic debris, which may be a very useful tool in diagnosis of tumor grades, especially in CNS, skin, Gyn., soft tissue, and GIST.
Antibody TypeRabbitt MonoclonalCloneEP233
IsotypeIgGReactivityParaffin, Frozen
Tonsil, Lymph Node
Histone H3 Phospho is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2524PredilutedReady-To-Use3.0 ml
BSB 2525PredilutedReady-To-Use7.0 ml
BSB 2526PredilutedReady-To-Use15.0 ml
BSB 2527Concentrated1:100-1:5000.1 ml
BSB 2528Concentrated1:100-1:5000.5 ml
BSB 2529Concentrated1:100-1:5001.0 ml
BSB 2530Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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