Histone H3 Phospho – Rabbit Polyclonal

Ihc Of Histone H3 Phospho On An Ffpe Breast Carcinoma Tissue

IHC of Histone H3 on an FFPE Breast Carcinoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationPhosphohistone-H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucelosomes of the “beads on a string” structure. In mammalian cells, phosphohistone H3 is negligible during interphase but reaches a maximum for chromatin condensation during mitosis.
Phosphohistone-H3 can serve as a mitotic marker to separate mitotic figures from apoptotic bodies and karyorrhectic debris, which may be a very useful tool in diagnosis of tumor grades, especially in CNS, skin, Gyn., soft tissue, and GIST.
Antibody TypeRabbit PolyclonalClonePolyclonal
IsotypeIgGReactivityParaffin, Frozen
LocalizationNuclearControlTonsil, Lymph Node
PresentationHistone H3 is a rabbit polyclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6821PredilutedReady-To-Use3.0 ml
BSB 6822PredilutedReady-To-Use7.0 ml
BSB 6823PredilutedReady-To-Use15.0 ml
BSB 6824Concentrated1:25-1:1000.1 ml
BSB 6825Concentrated1:25-1:1000.5 ml
BSB 6826Concentrated1:25-1:1001.0 ml
BSB 6827Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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