Granzyme B – RMab

Granzyme B Rmab Alt

IHC of Granzyme B on an FFPE Spleen Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationGranzymes are exogenous serine proteases that are released by cytoplasmic granules within cytotoxic T-cells and natural killer cells. Their purpose is to induce apoptosis within virus-infected cells, thus destroying them.
Anti-Granzyme B antibodies have been useful in diagnosing Natural Killer/T-cell Lymphoma, as well as Anaplastic Large Cell Lymphoma. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin’s Disease.
Antibody TypeRabbit MonoclonalCloneEP230
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmic (Granular)ControlLiver, Testis, Cervix, Tonsil, Lymph Node, Spleen
PresentationGranzyme B is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2405PredilutedReady-To-Use3.0 ml
BSB 2406PredilutedReady-To-Use7.0 ml
BSB 2407PredilutedReady-To-Use15.0 ml
BSB 2408Concentrated1:25-1:1000.1 ml
BSB 2409Concentrated1:25-1:1000.5 ml
BSB 2410Concentrated1:25-1:1001.0 ml
BSB 2411Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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