GCDFP-15 – RMab

SKU: 1bead773bda3 Categories: , , ,

Ihc Of Gcdfp-15 On An Ffpe Breast Carcinoma Tissue

IHC of GCDFP-15 on an FFPE Breast Carcinoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationGross Cystic Disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross Cystic Disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP-15. The cells within the body that produce GCDFP-15 appear to be restricted primarily to those with apocrine function such as breast cysts and in apocrine glands in the axilla, vulva, eyelid, and ear canal.
Studies have found GCDFP-15 to be a highly specific and sensitive marker for breast cancer. Approximately 70% of breast carcinomas stain positive with antibody to GCDFP-15. In contrast, Colorectal Carcinomas, as well as Mesotheliomas, do not stain with this antibody. Lung Adenocarcinomas rarely stain with this antibody.
Antibody TypeRabbit MonoclonalCloneEP95
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlBreast, Salivary Gland, Breast Carcinoma, Sweat Glands in Skin
PresentationGCDFP-15 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6765PredilutedReady-To-Use3.0 ml
BSB 6766PredilutedReady-To-Use7.0 ml
BSB 6767PredilutedReady-To-Use15.0 ml
BSB 6768Concentrated1:50-1:2000.1 ml
BSB 6769Concentrated1:50-1:2000.5 ml
BSB 6770Concentrated1:50-1:2001.0 ml
BSB 6771Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content