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Galectin-3 – MMab

Galectin 3 40X 1WG17 21 1 Colon

IHC of Galectin-3 on an FFPE Colon Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationGalectin-3 is a 31 kDa beta-galactosidase binding lectin. It has been associated with binding to the basement membrane glycoprotein laminin. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Anti-Galectin-3 has been demonstrated to be valuable in differentiating between benign and malignant thyroid neoplasms in both histologic sections and Fine Needle Aspiration Biopsy material. Anti-Galectin-3 antibody has also been useful in identifying Anaplastic Large Cell Lymphoma.
Antibody TypeMouse MonoclonalClone9C4
IsotypeIgG1ReactivityParaffin, Frozen
LocalizationCytoplasmicControlKidney, Testis, Salivary Gland, Breast, Tonsil, Colon, Papillary, Follcular Carcinoma of Thyroid
PresentationGalectin-3 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5540PredilutedReady-To-Use3.0 ml
BSB 5541PredilutedReady-To-Use7.0 ml
BSB 5542PredilutedReady-To-Use15.0 ml
BSB 5543Concentrated1:50-1:2000.1 ml
BSB 5544Concentrated1:50-1:2000.5 ml
BSB 5545Concentrated1:50-1:2001.0 ml
BSB 5546Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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