FOXP3 – Rabbit Polyclonal


IHC of FOXP3 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationFOXP3, also known as scurfin, is a protein involved in immune system responses. A member of the forkhead box protein family, FOXP3 appears to function as a transcription factor in the development and function of regulatory T cells. In regulatory T cell model systems, the FOXP3 transcription factor occupies the promoters of many important for regulatory T-cell function, and may repress transcription of key genes following stimulation of T cell receptors.
Alterations in numbers of regulatory T-cells — in particular those that express FOXP3 — are found in a number of disease states. Patients with tumors have a local relative excess of FOXP3 positive T cells which inhibits the body’s ability to suppress the formation of cancerous cells.
Antibody TypeRabbit PolyclonalClonePolyclonal
IsotypeIgGReactivityParaffin, Frozen
LocalizationNuclearControlColon, Tonsil, Lymph Node
PresentationFOXP3 is a rabbit polyclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6758PredilutedReady-To-Use3.0 ml
BSB 6759PredilutedReady-To-Use7.0 ml
BSB 6760PredilutedReady-To-Use15.0 ml
BSB 6761Concentrated1:25-1:1000.1 ml
BSB 6762Concentrated1:25-1:1000.5 ml
BSB 6763Concentrated1:25-1:1001.0 ml
BSB 6764Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content