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Desmin – MMab

SKU: a1992f07d42d Categories: , , , , ,

IHC of Desmin on an FFPE Skeletal Muscle Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Desmin is a type of intermediate filament found near the Z line in sarcomeres. Both vimentin and desmin are characteristics of mesenchymal cells. Desmin antibody detects a protein that is expressed by cells of normal smooth, skeletal and cardiac muscles. Light microscopy studies of desmin suggests that it is primarily located at or near the periphery of Z lines in striated muscle fibrils. In smooth muscle, Desmin interconnects cytoplasmic dense bodies with membranebound dense plaques. Desmin antibody reacts with Leiomyomas, Rhabdomyomas, and Perivascular cells of Glomus Tumors of the skin (if they are of myogenic nature). This antibody is used to demonstrate the myogenic components/derivation of tumors.
Antibody Type Mouse Monoclonal Clone D33
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Skeletal Muscle
Presentation Desmin antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5456 Prediluted Ready-To-Use 3.0 ml
BSB 5457 Prediluted Ready-To-Use 7.0 ml
BSB 5458 Prediluted Ready-To-Use 15.0 ml
BSB 5459 Concentrated 1:25-1:100 0.1 ml
BSB 5460 Concentrated 1:25-1:100 0.5 ml
BSB 5461 Concentrated 1:25-1:100 1.0 ml
BSB 5462 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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