Desmin – MMab

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Desmin Mmab

IHC of Desmin on an FFPE Skeletal Muscle Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationDesmin is a type of intermediate filament found near the Z line in sarcomeres. Both vimentin and desmin are characteristics of mesenchymal cells. Desmin antibody detects a protein that is expressed by cells of normal smooth, skeletal and cardiac muscles. Light microscopy studies of desmin suggests that it is primarily located at or near the periphery of Z lines in striated muscle fibrils. In smooth muscle, Desmin interconnects cytoplasmic dense bodies with membranebound dense plaques. Desmin antibody reacts with Leiomyomas, Rhabdomyomas, and Perivascular cells of Glomus Tumors of the skin (if they are of myogenic nature). This antibody is used to demonstrate the myogenic components/derivation of tumors.
Antibody TypeMouse MonoclonalCloneD33
IsotypeIgG1/KReactivityParaffin, Frozen
LocalizationCytoplasmicControlSkeletal Muscle
PresentationDesmin antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5456PredilutedReady-To-Use3.0 ml
BSB 5457PredilutedReady-To-Use7.0 ml
BSB 5458PredilutedReady-To-Use15.0 ml
BSB 5459Concentrated1:25-1:1000.1 ml
BSB 5460Concentrated1:25-1:1000.5 ml
BSB 5461Concentrated1:25-1:1001.0 ml
BSB 5462Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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