Cytokeratin 5 & 6 – RMab

Cytokeratin 5 6 Rmab

IHC of Cytokeratin 5 & 6 on an FFPE Mesothelioma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCytokeratin 5 (58 kDa) is a high-molecular weight, basic type of cytokeratin expressed in basal, intermediate and superficial-cell layers of stratified epithelia as well as transitional epithelia, complex epithelia, mesothelial cells and Mesothelioma. Cytokeratin 6 (56 kD) is also a high-molecular weight, basic type cytokeratin expressed by proliferating squamous epithelium often paired with Cytokeratin 16.
CK 5 and 6 are positively seen in nearly 100% of Malignant Mesotheliomas and are rarely seen in Lung Adenocarcinomas. CK 5 and 6 can positively be seen in undifferentiated Large-cell Carcinoma as well as Squamous Carcinoma. Fewer than 10% of Carcinomas of the breast, colon, and prostate stain positively for this marker. CK 5 and 6 have also been used successfully as a myoepithelial cell marker in the prostate to determine malignancy.
Antibody TypeRabbit MonoclonalCloneEP24/EP67
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlMesothelioma, Prostate
PresentationCK5/6 is a rabbit monoclonal cocktail antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6604PredilutedReady-To-Use3.0 ml
BSB 6605PredilutedReady-To-Use7.0 ml
BSB 6606PredilutedReady-To-Use15.0 ml
BSB 6607Concentrated1:25-1:1000.1 ml
BSB 6608Concentrated1:25-1:1000.5 ml
BSB 6609Concentrated1:25-1:1001.0 ml
BSB 6610Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content