Clusterin/Apoliprotein J – RMab

SKU: 67cc1cab0e07 Categories: , , , ,

Clusterin Apolipoprotein J

IHC of CLusterin/Apoliprotein J on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationThe Clusterin protein, also known as Apolipoprotein J, is a 75-80 kDa disulfide-linked heterodimeric protein containing about 30% of N-linked carbohydrate rich in sialic acid. It is a stress-induced cytoprotective chaperone protein regulated by HSF1 and functions similarly to a small heat-shock protein. Clusterin is distributed widely in human tissues and fluids, including normal epithelial cells, plasma, cerebrospinal fluid, breast milk, semen and urine. Clusterin has been implicated in a variety of activities including programmed cell death, regulation of complement mediated cell lysis, membrane recycling, cell-cell adhesion, and src induced transformation. As part of the attack complex of complement, it acts as a complement inhibitor.
Clusterin is expressed in a wide variety of hematopoietic and non-hematopoietic tumors. Overexpression of Clusterin is associated with poor prognosis in breast cancer and chemosensitivity in cervical cancer.
Antibody TypeRabbit MonoclonalCloneEP181
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlTonsil, Lymph Node, Placenta, Colon, Kidney, Brain, Liver
PresentationClusterin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6569PredilutedReady-To-Use3.0 ml
BSB 6570PredilutedReady-To-Use7.0 ml
BSB 6571PredilutedReady-To-Use15.0 ml
BSB 6572Concentrated1:25-1:1000.1 ml
BSB 6573Concentrated1:25-1:1000.5 ml
BSB 6574Concentrated1:25-1:1001.0 ml
BSB 6575Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content