CD8 – RMab

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3. 1. Ihc Of Cd8 On A Ffpe Spleen Tissue Webpage

IHC of CD8 on an FFPE Spleen Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and Explanation

CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule that is specific for the Class I MHC protein. To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8-β chain, both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. CD8 is a T-cell marker for the detection of cytotoxic/suppressor cells of blood lymphocytes. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells and bone marrow cells. This antibody is used to distinguish between reactive and neoplastic T-cells.

Antibody TypeRabbit MonoclonalCloneEP334
IsotypeIgGReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node, Liver, Colon
PresentationCD8 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2845PredilutedReady-To-Use3.0 ml
BSB 2846PredilutedReady-To-Use7.0 ml
BSB 2847PredilutedReady-To-Use15.0 ml
BSB 2848Concentrated1:50-1:2000.1 ml
BSB 2849Concentrated1:50-1:2000.5 ml
BSB 2850Concentrated1:50-1:2001.0 ml
BSB 2851Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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