CD57 – MMab

Ihc Of Cd57 On An Ffpe Tonsil Tissue

IHC of CD57 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD57 (NK-1) recognizes an oligosaccharide (MW 100-110 kDa) antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system. Follicular Center-cell Lymphomas often contain many NK cells within the neoplastic follicles. NK-1 reportedly also reacts with a variety of cell types in non-lymphoid tissues. NK-1 stains neuroendocrine cells and their tumors, including Carcinoid Tumor and Medulloblastomas. NK-1 also reacts with a variety of cell types in non-lymphoid tissues, including Neurofibroma, Ganglioneuroma, and Prostate Carcinoma.
Antibody TypeMouse MonoclonalCloneBSB-10 (CD57/B8)
IsotypeIgM/KReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node
PresentationCD57 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5274PredilutedReady-To-Use3.0 ml
BSB 5275PredilutedReady-To-Use7.0 ml
BSB 5276PredilutedReady-To-Use15.0 ml
BSB 5277Concentrated1:100-1:5000.1 ml
BSB 5278Concentrated1:100-1:5000.5 ml
BSB 5279Concentrated1:100-1:5001.0 ml
BSB 5280Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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