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CD56 – MMab

IHC of CD56 on an FFPE Neuroblastoma Tissue

IHC of CD56 on an FFPE Neuroblastoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD56 or Neural-Cell Adhesion Molecule (NCAM) is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. CD56 has been implicated in cell-cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory. Normal cells that stain positively for CD56 include NK cells, activated T-cells, brain and cerebellum, and neuroendocrine tissues. Tumors that are CD56-positive are Myeloma, Myeloid Leukemia, Neuroendocrine tumors, Wilm’s Tumor, Adult Neuroblastoma, NK/T cell Lymphomas, Pancreatic Acinar-cell Carcinoma, Pheochromocytoma, and Small-cell Lung Carcinoma. It is also expressed on some mesodermally-derived tumors (Rhabdomyosarcoma). Ewing’s Sarcoma/PNET is CD56-negative.
Antibody TypeMouse MonoclonalClone123C3.D5
IsotypeIgG1/KReactivityParaffin, Frozen
LocalizationMembranousControlPancreas, Tonsil, Neuroblastoma, Brain, Thyroid, Prostate, Colon, Lung SCC
PresentationCD56 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5267PredilutedReady-To-Use3.0 ml
BSB 5268PredilutedReady-To-Use7.0 ml
BSB 5269PredilutedReady-To-Use15.0 ml
BSB 5270Concentrated1:250-1:10000.1 ml
BSB 5271Concentrated1:250-1:10000.5 ml
BSB 5272Concentrated1:250-1:10001.0 ml
BSB 5273Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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