CD45 – MMab

Ihc Of Cd45 On An Ffpe Tonsil Tissue

IHC of CD45 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationThe CD45 antigen is a protein which was originally called Leukocyte Common Antigen. It is a Type I transmembrane protein which is in various forms present on all differentiated hematopoietic cells except erythrocytes and assists in the activation of those cells (a form of co-stimulation). It is expressed in Lymphomas, B-cell Chronic Lymphocytic Leukemia, Hairy Cell Leukemia, and Acute Non-lymphocytic Leukemia. CD45 is a monoclonal antibody that is routinely used to aid in the differential diagnosis of undifferentiated neoplasms, whenever malignant Lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody; thus, a positive result is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin’s Disease, some T-cell Lymphomas and some Leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is exclusively expressed by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes, erythrocytes and plasma cell precursors.
Antibody TypeMouse MonoclonalClone2B11 & PD7/26
IsotypeIgG1/KReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node, Spleen, Thymus
PresentationCD45 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5246PredilutedReady-To-Use3.0 ml
BSB 5247PredilutedReady-To-Use7.0 ml
BSB 5248PredilutedReady-To-Use15.0 ml
BSB 5249Concentrated1:250-1:10000.1 ml
BSB 5250Concentrated1:250-1:10000.5 ml
BSB 5251Concentrated1:250-1:10001.0 ml
BSB 5252Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content