CD43 – MMab

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Ihc Of Cd43 On An Ffpe Tonsil Tissue

IHC of CD43 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use.
Summary and ExplanationCD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is one of the major glycoproteins expressed in all thymocytes and T-cells. It plays a role in the physicochemical properties of the T-cell surface and in lectin binding. During T-cell activation, CD43 is actively removed from the T-cell antigen-presenting cell contact site, suggesting a negative regulatory role in adaptive immune response. This antibody has been found useful in identification and classification of T-cell malignancies and low grade B-cell Lymphomas. CD43 expression is seen in some cases of B-cell Lymphocytic Lymphoma and Centrocytic Lymphoma. When used in combination with CD45 and CD20, effective immunophenotyping of the majority of Lymphomas can be obtained. Co-staining of a lymphoid infiltrate with CD20 and CD3 argues against a reactive process and favors Lymphoma.
Antibody TypeMouse MonoclonalCloneMT1
IsotypeIgG1ReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node
PresentationCD43 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5239PredilutedReady-To-Use3.0 ml
BSB 5240PredilutedReady-To-Use7.0 ml
BSB 5241PredilutedReady-To-Use15.0 ml
BSB 5242Concentrated1:100-1:5000.1 ml
BSB 5243Concentrated1:100-1:5000.5 ml
BSB 5244Concentrated1:100-1:5001.0 ml
BSB 5245Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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