CD25 – RMab

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Cd25 Ivd

IHC of CD25 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. Studies have shown that a large proportion of resting memory T cells constitutively express CD25. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression. CD25 is also utilized in cases of mastocytosis
Antibody TypeRabbit MonoclonalCloneRBT-CD25
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmic, MembranousControlTonsil, Small Bowel, Spleen, Mastocytosis,Hodgkin’s Lymphoma
PresentationCD25 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 2454PredilutedReady-To-Use3.0 ml
BSB 2455PredilutedReady-To-Use7.0 ml
BSB 2456PredilutedReady-To-Use15.0 ml
BSB 2457Concentrated1:10-1:500.1 ml
BSB 2458Concentrated1:10-1:500.5 ml
BSB 2459Concentrated1:10-1:501.0 ml
BSB 2460Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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